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Immunoglobulin G (IgG) in Urine, Mass Concentration (Nephrogram)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody found in your urine. It helps assess kidney function and detect conditions like proteinuria or immune-related disorders.

Quick summary

["IgG in urine can signal kidney issues or immune system activity beyond blood tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
106809-7
Short code
IgG1 BldCo Neph-mCnc
Synonyms
IgG1 BldCo Neph-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
nephelometry
CPT
82784
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like frequent urination, swelling, or if they suspect conditions such as kidney disease, immune disorders, or certain infections. It can also be part of a broader evaluation for unexplained protein in urine.

What to Expect Before the Test

No special preparation is needed for this urine test. You may collect a random urine sample in a clean container. If ordered as part of a 24-hour collection, you’ll need to collect all urine over a full day.

What the Test Results Mean

Elevated IgG in urine may indicate kidney problems (such as nephrotic syndrome), immune system activity (like certain infections or autoimmune diseases), or other metabolic conditions. Abnormal results will be discussed with your provider to guide further testing or treatment.

Common Conditions Monitored

This test is often used alongside other urine tests (like proteinuria) to diagnose or monitor conditions such as glomerulonephritis, multiple myeloma, or chronic kidney disease. It helps track how well your kidneys are filtering waste and immune proteins.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG in Urine

Frequently asked questions

What does a positive or abnormal result mean?
An abnormal result (higher or lower than expected) won’t be definitive on its own. Your provider will review it alongside your medical history, symptoms, and other tests to determine next steps, such as additional imaging, bloodwork, or specialized kidney function tests.
Can diet or hydration affect this test?
Dietary changes or hydration levels may indirectly influence urine concentration, but they typically don’t directly alter IgG levels in urine. Stick to your usual routine unless instructed otherwise by your provider.
How often should this test be repeated?
Frequency depends on your condition and provider’s recommendations. Some patients with chronic kidney disease or immune disorders may need periodic monitoring, while others may only need this test once as part of a diagnostic evaluation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy