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24-Hour Urinary Immunoglobulin G (IgG) Excretion

Published: August 9, 2026Updated: August 16, 2026

This test measures how much Immunoglobulin G (IgG), a type of antibody, is excreted in your urine over a 24-hour period. It helps assess kidney function and potential immune system or protein-related conditions.

Quick summary

["This test helps evaluate kidney health and protein loss in urine over a full day’s output."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47083-1
Short code
IgG 24h Ur-mCnc
Synonyms
IgG 24h Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like frequent urination, swelling, or signs of kidney issues. It can also be used to monitor conditions affecting protein levels in urine, such as certain kidney diseases or immune disorders.

What to Expect Before the Test

No special preparation is needed. Collect all urine for 24 hours in a clean container. Drink plenty of water to ensure full urine output, but avoid excessive diuretics unless instructed otherwise.

What the Test Involves

You’ll provide a full 24-hour urine sample, typically starting after midnight of one day and ending just before midnight the next. The sample is sent to a lab for analysis.

What the Results Mean

Results show the total IgG amount excreted in urine. Elevated levels may indicate kidney problems (like nephrotic syndrome) or conditions causing protein loss, while normal levels suggest healthy protein filtration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24h IgG Urine

Frequently asked questions

How often should I expect this test?
Your doctor will determine frequency based on your symptoms, diagnosis, or treatment plan. It may be done occasionally or regularly depending on your condition.
What does a high or low IgG urine result mean?
A high result may signal kidney damage or protein loss, while a low result is less concerning unless part of a broader evaluation for immune function. Always discuss results with your provider.
Can I take medications before this test?
Some medications (like NSAIDs) may affect urine protein levels. Ask your provider if you should avoid them or adjust timing before collecting your sample.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy