24-Hour Urine Immunoglobulin G (IgG) Excretion Rate
This test measures the amount of IgG, an antibody, excreted in urine over a 24-hour period. It is primarily used to evaluate urinary protein loss and kidney function.
["The result estimates how much IgG your kidneys are losing in the urine over one day."]
Key facts at a glance
- LOINC
- 55923-7
- Short code
- IgG 24h Ur-mRate
- Synonyms
- IgG 24h Ur-mRate
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What the Test Measures
Immunoglobulin G is a type of antibody that normally circulates in the blood. Healthy kidneys filter the blood while retaining most antibodies, so only small amounts of IgG should appear in urine.
Why the Test Is Performed
A 24-hour urine IgG rate may be used to assess abnormal protein loss through the kidneys. It can support evaluation of suspected kidney inflammation, filtration-barrier damage, or conditions that affect urine protein production.
How the Sample Is Collected
Urine is collected for a full 24 hours, usually in a labeled container provided by the laboratory or clinic. The collection period, start time, end time, and any missed samples should be recorded and reported.
Factors That May Affect the Result
Collection errors, incomplete urine samples, unusually high or low fluid intake, illness, and medications that affect kidney function or urine protein excretion can influence the result. The laboratory's collection instructions should be followed carefully.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical significance: An elevated 24-hour urine IgG rate may indicate increased passage of antibodies through the kidneys, which can occur with glomerular or other kidney disease. A low or undetectable rate does not necessarily represent disease. Results should be interpreted with kidney function tests, urine protein measurements, symptoms, medications, and other clinical findings.
Short name
24-Hour Urine IgG Rate
Frequently asked questions
Why is a 24-hour urine collection needed?
What can cause an elevated urine IgG rate?
Does an abnormal result diagnose a specific kidney disease?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy