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Immunoglobulin G (IgG) 24-Hour Urine Collection (Total Protein or Specific Protein)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of protein found in urine, over a 24-hour period. It helps assess kidney function and detect protein loss in urine, which may indicate conditions like kidney disease or other health issues.

Quick summary

["This test helps monitor kidney health by checking for excessive protein in urine, often linked to IgG-related kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44595-7
Short code
IgG 24h Ur Ql IFE
Synonyms
IgG 24h Ur Ql IFE
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immunofixation
CPT
82784
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like swelling, frequent urination, or unexplained weight changes. It’s also used to monitor kidney function in people with conditions like diabetes, high blood pressure, or kidney disease. Sometimes, it’s part of a broader evaluation for unexplained protein in urine.

What to Expect Before the Test

You’ll need to collect all urine for 24 hours in a special container. Drink plenty of fluids to ensure a full collection. Avoid certain medications or foods that might affect protein levels, as instructed by your healthcare provider.

What the Test Results Mean

Higher-than-normal IgG in urine may suggest kidney damage or disease. Lower-than-normal levels could indicate dehydration or other health issues. Your doctor will interpret results in the context of your medical history and other tests.

Common Conditions This Test Helps Diagnose

Excessive IgG in urine can signal kidney problems like nephrotic syndrome, glomerulonephritis, or other protein-losing conditions. It may also help identify early kidney damage in people with risk factors like diabetes or high blood pressure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

IgG in urine is typically filtered by the kidneys. If present in abnormal amounts, it may indicate impaired kidney function or specific kidney diseases. Early detection can help manage conditions like proteinuria (protein in urine) and guide treatment decisions.

Short name

IgG Urine Protein Profile (24h)

Frequently asked questions

What causes IgG to appear in urine?
IgG in urine can appear due to kidney diseases (e.g., glomerulonephritis), certain infections, or conditions like multiple myeloma. Stress, high blood pressure, or diabetes may also contribute. Always discuss symptoms with your doctor.
How often should this test be repeated?
Your doctor will determine how often to repeat this test based on your health status. If you have kidney disease or risk factors, follow-up may be scheduled every few months to monitor changes.
Can diet or medications affect this test?
Yes, certain foods (e.g., high-protein diets), medications (e.g., NSAIDs), or supplements may influence protein levels. Ask your doctor or lab staff about restrictions before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy