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Immunoglobulin G (IgG) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody found in your blood. IgG helps protect your body from infections and plays a key role in long-term immunity.

Quick summary

["IgG helps fight infections and supports long-term immunity by identifying and neutralizing harmful substances in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6782-7
Short code
IgG/Alb Ser
Synonyms
IgG/Alb Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin G (IgG)?

IgG is the most common type of antibody in your blood. Antibodies are proteins that help your immune system recognize and fight off bacteria, viruses, and other invaders. IgG is particularly important because it can cross the placenta to provide passive immunity to your baby during pregnancy and early life. It also remains in your body for a long time after an infection has passed, providing ongoing protection.

Why Might You Need This Test?

Your doctor may order an IgG test to check for low or high levels, which can indicate conditions like immune deficiencies, infections, or certain autoimmune diseases. It may also be used to monitor treatment responses in people with chronic illnesses or to assess immune function in newborns or infants.

When Is This Test Done?

This test is typically performed by drawing blood from a vein in your arm. The blood sample is then sent to a lab for analysis. Results are usually available within a few days, depending on the lab’s processing time.

What Does the Test Tell You?

IgG levels can provide clues about your immune system’s strength. Low IgG levels might suggest a weakened immune response, while very high levels could indicate chronic infections, certain cancers, or other health conditions. Your doctor will interpret the results in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low IgG levels can be associated with conditions such as common variable immunodeficiency (CVID), HIV/AIDS, or other immune deficiencies. High IgG levels may suggest chronic infections, inflammatory diseases, or certain types of cancer, such as multiple myeloma. Monitoring IgG levels can also help track how well certain treatments are working for conditions like autoimmune diseases or infections.

Short name

IgG Level

Frequently asked questions

What Are Common Reasons for This Test?
Your doctor might recommend this test if you have symptoms like frequent infections, slow wound healing, or unexplained fatigue. It may also be part of a broader evaluation for immune-related conditions or before certain medical procedures.
How Long Does It Take to Get Results?
Results are usually available within 2 to 5 business days, depending on the lab’s workflow and your healthcare provider’s request. Your doctor will contact you once the results are ready.
Can I Eat or Drink Before the Test?
You can typically eat and drink normally before this test unless your doctor specifies otherwise. Avoiding alcohol or certain medications for a few hours before the blood draw may help ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy