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Immunoglobulin G (IgG) in canine serum (canine anti-dog serum IgG concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody, in your dog’s blood serum. IgG is important for long-term immunity and protecting against infections.

Quick summary

["IgG helps fight infections and provides long-lasting immunity in dogs."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24432-7
Short code
IgG Canine Ser ID-mCnc
Synonyms
IgG Canine Ser ID-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-diffusion
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your veterinarian may recommend this test to assess your dog’s immune response, especially after vaccination, to monitor immune function, or to diagnose conditions like immunodeficiency. It can also help evaluate how well a dog’s body is producing antibodies in response to specific antigens (substances like bacteria or viruses).

What to Expect Before the Test

No special preparation is needed for this blood test. Your dog may have a small needle inserted into a vein (usually in the paw or ear) to collect a blood sample. The process is quick and usually painless. If your dog is anxious, your vet may suggest calming aids or a sedative beforehand.

What Happens During the Test?

The collected blood sample is sent to a lab where it is analyzed to measure the IgG concentration. The test uses an immunoassay method to detect and quantify the antibodies present in the serum.

What Are the Possible Results?

Results are reported as a mass concentration (e.g., grams per liter). While reference ranges can vary by lab, lower than expected IgG levels may indicate weakened immunity, while higher levels might suggest an overactive immune response or chronic infection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

IgG Antibody Level (Canine)

Frequently asked questions

What Does a Low IgG Level Mean?
A low IgG level in dogs can signal an immune deficiency, making them more susceptible to infections. This may occur in congenital conditions, autoimmune diseases, or after certain treatments like chemotherapy. Your vet may recommend additional tests or treatments to support your dog’s immune system.
What Does a High IgG Level Mean?
High IgG levels can be seen in chronic infections, inflammatory conditions, or as a reaction to certain vaccines or allergens. While not always concerning, persistent high levels should be evaluated to rule out underlying health issues.
How Often Should This Test Be Done?
The frequency depends on your dog’s health status. Dogs with known immune disorders may need regular monitoring, while healthy dogs with recent vaccinations might only need this test occasionally, as directed by their vet.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy