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Immunoglobulin G (IgG) Protein Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG is important for fighting infections and long-term immunity.

Quick summary

["IgG helps protect your body from diseases and infections over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54901-4
Short code
IgG Prt-mCnc
Synonyms
IgG Prt-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does IgG Serve in Your Body?

IgG antibodies are the most abundant type of antibody in your blood. They play a key role in providing long-term immunity by helping your immune system remember past infections, which can prevent future illnesses. IgG is also involved in protecting against toxins and foreign substances, such as bacteria and viruses.

When Might You Need This Test?

Doctors may order an IgG test to check for low or high levels, which can happen in conditions like immune deficiencies, chronic infections, or certain autoimmune diseases. It may also be used to monitor treatment responses in patients with weakened immune systems.

Common Reasons for Testing

Common reasons include diagnosing or managing conditions such as HIV, certain cancers (like lymphoma), chronic infections, or immune system disorders. It can also be part of routine monitoring for patients on immunosuppressive therapy.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. If you are on blood thinners or have a history of bleeding issues, let your healthcare provider know.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low IgG levels may indicate a weakened immune system, potentially due to conditions like primary immunodeficiency, HIV/AIDS, or certain cancers. High IgG levels can sometimes be seen in chronic infections, autoimmune diseases, or as a response to repeated vaccinations. Monitoring IgG levels helps healthcare providers tailor treatments to support immune function and manage health conditions effectively.

Short name

IgG Level

Frequently asked questions

Why might my IgG test results be abnormal?
Abnormal IgG levels can be due to underlying health conditions such as immune deficiencies, chronic infections, or autoimmune diseases. It could also be related to certain medications or treatments that affect your immune system. Always discuss any concerns with your healthcare provider.
How often should I get this test?
The frequency of IgG testing depends on your medical condition and treatment plan. Your healthcare provider will determine how often you need this test based on your individual needs and ongoing health monitoring.
Can lifestyle changes affect my IgG levels?
While lifestyle factors like diet and exercise can support overall immune health, they do not directly influence IgG levels. However, maintaining a healthy lifestyle can help your immune system function better, which may indirectly support balanced antibody levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy