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Immunoglobulin Synthesis Rate in Serum (Electrophoresis-Based)

Published: August 9, 2026Updated: August 16, 2026

This test measures how efficiently your body produces antibodies (immunoglobulins) in serum, often assessed through protein electrophoresis.

Quick summary

["Helps evaluate immune function and detect abnormalities in antibody production."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13456-9
Short code
IgG Synth Rate Ser+CSF-aCnc
Synonyms
IgG Synth Rate Ser+CSF-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like frequent infections, unexplained fatigue, or signs of immune system dysfunction. It can also be part of a broader evaluation for conditions like chronic infections, autoimmune diseases, or certain blood disorders.

How the Test Works

The test involves analyzing serum proteins using electrophoresis, which separates different types of proteins based on size and charge. The rate of immunoglobulin synthesis is inferred from the protein profile, often compared to standard patterns.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The serum portion is separated and sent to the lab for analysis. This test does not require fasting.

What to Expect Before the Test

There are no special preparations needed. You may experience mild discomfort from the needle, but it usually goes away quickly. Avoid heavy exercise or alcohol for 24 hours before the test if instructed by your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Ig Synthesis Rate

Frequently asked questions

What does an abnormal result mean?
An abnormal result doesn’t always mean you have a specific disease. It may prompt further testing, such as additional blood work, imaging, or consultations with specialists like an immunologist. Your doctor will discuss the results in detail and determine the next steps based on your overall health and symptoms.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will contact you once the results are ready.
Can I eat or drink before this test?
You can eat and drink normally before this test unless your doctor specifies otherwise. Blood tests like this do not require fasting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy