IgG synthesis rate calculated from serum immunoglobulin levels
This test measures how efficiently your body produces Immunoglobulin G (IgG), a key antibody protein that helps fight infections and supports immune function. It’s often calculated from a baseline IgG measurement.
["Assesses immune system productivity and potential IgG deficiency risks."]
Key facts at a glance
- LOINC
- 14116-8
- Short code
- IgG Synth Rate Ser+CSF Calc-mRate
- Synonyms
- IgG Synth Rate Ser+CSF Calc-mRate
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- calculated
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your doctor may recommend this test if you have symptoms of a weakened immune system, such as frequent infections, unexplained bruising, or prolonged healing. It could also be part of an evaluation for conditions like common variable immunodeficiency (CVID) or other antibody-related disorders.
How the Test Works
A blood sample is drawn to measure your baseline IgG levels. The test then calculates the rate at which your body produces IgG over time, often using a mathematical model based on your immune response profile.
What to Expect Before the Test
No special preparation is needed, but avoid taking immune-modifying medications (like steroids) 2–3 days before your test, as they can affect IgG levels. Let your doctor know about any medications or supplements you’re taking.
What the Results Mean
A lower-than-expected IgG synthesis rate may indicate an immune system that doesn’t produce enough antibodies, increasing your risk of infections. A higher-than-expected rate might suggest overactive immune activity or other metabolic factors. Your doctor will interpret results in the context of your overall health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
IgG Synthesis Rate
Frequently asked questions
What causes IgG synthesis rate to be low?
What should I do if my IgG synthesis rate is abnormal?
Does diet affect IgG synthesis?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy