Immunoglobulin G (IgG) Mutation Status in Whole Blood
This test checks for specific genetic mutations in your IgG antibodies, which may affect how your immune system responds to infections or certain diseases.
["Understanding IgG genetic variations can help identify potential immune-related conditions or tailor treatments for better outcomes."]
Key facts at a glance
- LOINC
- 107551-4
- Short code
- IGH mutation status Bld/T
- Synonyms
- IGH mutation status Bld/T
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
This test analyzes genetic mutations in the genes responsible for producing IgG antibodies. IgG is the most common antibody in your blood, playing a key role in defending against bacteria and viruses. Mutations in these genes could influence antibody function or immune system efficiency.
Why Might You Need This Test?
Your healthcare provider may recommend this test if you have symptoms like frequent infections, unusual immune responses, or if you’re being evaluated for conditions like immunodeficiency, autoimmune diseases, or certain cancers that may involve antibody-related mutations.
Sample Collection and Preparation
A small amount of whole blood will be drawn from your arm. This sample is then processed to extract genetic material for mutation analysis. No special preparation is needed, but avoid strenuous activity before the test.
What Are the Possible Results?
Results will indicate whether specific IgG-related mutations are present or absent. The interpretation depends on clinical context and may involve comparing your results to known mutation profiles in similar conditions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
IgG mutation status can help diagnose or monitor conditions affecting antibody production or function. For example, certain mutations may be linked to primary immunodeficiency disorders, where the immune system doesn’t work as expected. Identifying these mutations can guide treatment plans, such as immune therapy or targeted medications.
Short name
IgG Mutation Screening
Frequently asked questions
How long will it take to get my results?
What does a positive or negative result mean?
Can I influence the outcome of this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy