24-Hour Urinary Immunoglobulin G (IgG) Excretion Rate

Why This Test Is Done

Your healthcare provider may order this test if they suspect kidney disease, such as glomerulonephritis, or if you have symptoms like frequent urination, swelling, or unexplained protein in your urine. It can also be used in research or specialized diagnostic scenarios where long-term antibody excretion patterns are important.

What to Expect Before the Test

You’ll typically collect all your urine for a full 24-hour period in a special container. Drink plenty of fluids to ensure normal urine output, but avoid excessive diuretics unless instructed. Follow any specific instructions your lab provides to ensure accurate results.

During the Test Process

Once your urine sample is complete, it’s sent to a lab for analysis. The test measures the amount of IgG in your urine using a specialized immunoassay method. Results are compared to standard reference ranges to determine if levels are within normal limits or if further evaluation is needed.

What the Results Mean

Higher-than-normal IgG excretion in urine may indicate kidney issues, such as protein loss, or certain immune system disorders. Lower-than-normal levels might suggest dehydration or other conditions affecting antibody presence in urine. Your healthcare provider will interpret results in the context of your overall health and symptoms.