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: Immunoglobulin M (IgM) Electrophoresis, Serum, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

: This test measures the amount and pattern of immunoglobulin M (IgM) proteins in a serum sample using electrophoresis, a technique that separates proteins by their electrical charge and movement.

Quick summary

[": IgM serum electrophoresis helps your care team see how much IgM is present and whether it appears in an abnormal pattern."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55925-2
Short code
IgM Ser Elph-mCnc
Synonyms
IgM Ser Elph-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
electrophoresis
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What Is Being Measured

: Immunoglobulins are antibody proteins made by your immune system. IgM is the type produced early in an immune response. This test looks at the IgM present in the liquid portion of your blood (serum) and reports its concentration and separation pattern.

: How Electrophoresis Works

: In electrophoresis, proteins in your serum are placed on a special medium and exposed to an electric field. Different proteins move at different speeds and separate into bands. The laboratory then measures the IgM portion, giving information about its amount and distribution.

: Why Your Clinician May Order It

: Your clinician may order this test when checking the immune system, investigating an unusual protein pattern, or monitoring a condition associated with increased IgM. It is often interpreted together with other immunoglobulin and protein electrophoresis results.

: What to Expect

: The test uses a routine blood draw, usually from a vein in your arm. Most people do not need special preparation unless your clinician gives other instructions. Results are interpreted in the context of your symptoms, history, and other laboratory findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: IgM electrophoresis can help identify increases or abnormal patterns of IgM, which may be relevant to immune disorders or certain blood conditions. Because results depend on many factors, they should always be interpreted by a clinician alongside other tests rather than in isolation.

Short name

: IgM Serum Electrophoresis

Frequently asked questions

: Does this test diagnose a specific disease on its own?
: No. It provides information about IgM amount and pattern; diagnosis usually requires combining it with other tests, your medical history, and a clinical examination.
: Do I need to fast before this test?
: Fasting is generally not required for immunoglobulin testing, but follow any instructions your clinician or laboratory provides.
: Is the blood draw painful?
: You may feel a brief pinch when the needle is inserted, and some mild soreness or bruising can occur afterward, but the draw is usually quick and well tolerated.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy