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Interleukin-1 Alpha, Fluid — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of IL-1α in a fluid collected from the body, such as fluid around a joint or in a body cavity.

Quick summary

["This test measures IL-1α in a body fluid to help evaluate inflammation at the sampled site."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
70076-5
Short code
Il1Alpha Fld-mCnc
Synonyms
Il1Alpha Fld-mCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
44
Ref high
147
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84075
SNOMED
27550007
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

Interleukin-1 alpha (IL-1α) is a signaling protein involved in inflammation and immune responses. This test measures its mass concentration in a body fluid, such as synovial, pleural, peritoneal, or cerebrospinal fluid.

Why might I need this test?

A clinician may order this test when inflammation or infection is suspected in a particular area of the body. The result can help support or narrow the assessment of conditions affecting the sampled fluid.

How is the test performed?

A healthcare professional collects fluid from the relevant body site using a sterile needle or another appropriate collection method. The laboratory then measures the IL-1α concentration using an immunoassay or a comparable testing method.

How do I prepare for the test?

Preparation depends on the fluid being collected and the procedure used. Follow the clinic's instructions, tell the healthcare team about medicines or bleeding disorders, and do not stop medications unless specifically advised.

Reference range

Adult: 44-147 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher IL-1α concentration may be associated with inflammation, infection, or an immune response at the site where the fluid was collected. Results must be interpreted with the fluid type, symptoms, examination findings, and other laboratory tests because IL-1α is not specific to one condition. An unexpected result should be discussed with the ordering clinician.

Short name

Interleukin-1 Alpha (IL-1α), Fluid

Frequently asked questions

Does this test show whether I have inflammation throughout my body?
No. It measures IL-1α only in the fluid sample collected, so it primarily provides information about inflammation or immune activity at that site.
Is fasting or special preparation required?
There is generally no special preparation for the laboratory measurement itself, but collection procedures may have specific requirements. Follow the instructions provided by the healthcare professional performing the fluid collection.
Can IL-1α results diagnose a specific condition by themselves?
No. IL-1α is one of several markers that may rise in many inflammatory or infectious conditions. Your clinician will interpret it alongside your symptoms, examination, imaging, and other test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy