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Interleukin-2 Receptor (IL-2R) Serum/Plasma Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of interleukin-2 receptor protein in your blood. IL-2R helps regulate immune responses by binding to interleukin-2, a protein involved in T-cell activation.

Quick summary

["IL-2R levels may indicate immune activity or potential autoimmune conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24458-2
Short code
Il2Recep SerPl-mCnc
Synonyms
Il2Recep SerPl-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to evaluate immune function, assess autoimmune diseases (such as rheumatoid arthritis or lupus), or monitor treatment responses in conditions where IL-2 plays a role. It can also help diagnose or monitor certain cancers or infections.

What Does the Result Mean?

Results are not typically provided as a single reference range since IL-2R levels can vary widely based on health status, immune activity, and other factors. Elevated levels may suggest overactive immune responses, while lower levels could indicate immune suppression or certain diseases.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum or plasma for testing. This test does not require fasting.

Common Conditions Monitored

IL-2R levels are often checked in patients with autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus), certain cancers (e.g., lymphoma), or after immune-modifying treatments. It may also be used in research or specialized clinical settings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

IL-2R Serum/Plasma Level

Frequently asked questions

What Are My Next Steps If My Result Is Abnormal?
If your IL-2R level is outside expected ranges, your healthcare provider will discuss further testing or follow-up to determine the cause. They may adjust treatment plans, recommend additional blood tests, or refer you to a specialist for deeper evaluation.
How Often Should I Have This Test?
The frequency depends on your medical condition, treatment plan, and healthcare provider’s recommendations. Some patients may need this test periodically, while others may only require it once or during specific phases of treatment.
Is There Any Preparation Needed Before the Test?
No special preparation is needed. You can eat and drink normally on the day of the test, but avoid smoking or strenuous activity right before your blood draw.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy