Serum/plasma concentration of imipenem (antibiotic drug)
This test measures the amount of the antibiotic imipenem in your blood to check how your body is responding to treatment.
["Your doctor may use this test to monitor your antibiotic levels for safety and effectiveness."]
Key facts at a glance
- LOINC
- 73334-5
- Short code
- Imipenem ind plt IgG SerPl Ql FC
- Synonyms
- Imipenem ind plt IgG SerPl Ql FC
- Category
- hematology
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Imipenem is a broad-spectrum antibiotic used to treat serious bacterial infections. Your healthcare provider may order this test if you’re receiving intravenous (IV) imipenem treatment, especially if you have kidney issues or are at risk of developing resistance. It helps ensure the right dose is given and that the drug stays effective without causing harmful side effects.
What to Expect Before the Test
No special preparation is needed. You may have blood drawn from a vein in your arm, typically in a doctor’s office, clinic, or lab. The process is quick and usually painless, though you might feel a slight pinch. If you’re on IV imipenem, your blood sample may be taken during or shortly after your infusion.
What the Test Results Mean
Results are used to guide dosing adjustments. Low levels may indicate the drug isn’t working well, while dangerously high levels could signal toxicity. Your provider will interpret results in the context of your medical condition, other medications, and kidney function.
Possible Side Effects or Risks
While rare, imipenem can cause side effects like nausea, diarrhea, or allergic reactions. Blood tests like this help prevent overuse or underuse, reducing risks. If you experience severe reactions (e.g., rash, swelling, trouble breathing), seek medical attention immediately.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is critical for patients receiving IV imipenem, particularly those with kidney problems or those at higher risk of antibiotic resistance. Optimal dosing depends on balancing antibiotic effectiveness against potential toxicity. Unmonitored levels can lead to ineffective treatment (e.g., infection persistence) or harm (e.g., kidney damage). Regular monitoring ensures the drug remains therapeutic while minimizing adverse effects.
Short name
Imipenem Level
Frequently asked questions
Why might my doctor order this test?
What does a low or high imipenem level mean?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy