Neutrophil count in cerebrospinal fluid (CSF) by automated cell differential
This test measures the number of neutrophils, a type of white blood cell, in your cerebrospinal fluid (CSF). Neutrophils help fight infections and inflammation in the central nervous system.
["Assessing your CSF for neutrophil levels can help diagnose or monitor conditions affecting the brain or spinal cord."]
Key facts at a glance
- LOINC
- 69006-5
- Short code
- Imm Granulocytes NFr CSF
- Synonyms
- Imm Granulocytes NFr CSF
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Doctors may order this test if you have symptoms like severe headaches, neck stiffness, fever, or neurological issues that suggest an infection or inflammation in the brain or spinal cord. It can also be part of a routine evaluation for conditions like meningitis, encephalitis, or other infections.
What to Expect Before the Test
You’ll likely undergo a lumbar puncture (spinal tap) where a small needle is inserted into your lower back to collect CSF. The procedure is usually quick and done while you’re lying on your side. You may feel a brief pinch, but it’s generally not painful.
What the Test Results Mean
High neutrophil counts in CSF may indicate an infection (such as bacterial meningitis) or inflammation. Low or normal counts could suggest viral infections, autoimmune conditions, or other non-infectious causes. Your doctor will interpret results in the context of your symptoms and overall health.
Common Conditions Monitored
This test helps diagnose or monitor conditions like bacterial meningitis, encephalitis, subarachnoid hemorrhage, or other inflammatory or infectious processes in the central nervous system.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Neutrophils in CSF
Short name
CSF Neutrophils
Frequently asked questions
What causes elevated neutrophil levels in CSF?
What does a normal or low neutrophil count in CSF suggest?
How often should this test be repeated?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy