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Immunoassay for Immunoglobulin E (IgE) Antibody, Total

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of Immunoglobulin E (IgE) antibodies in your blood. IgE is linked to allergic reactions and certain immune conditions.

Quick summary

["IgE levels help identify allergies or immune-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51636-9
Short code
Imm Retics #
Synonyms
Imm Retics #
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like sneezing, itching, skin rashes, or breathing difficulties that suggest allergies. It could also be used to monitor conditions like asthma, eczema, or chronic urticaria (hives). In some cases, it may help diagnose parasitic infections or certain immune disorders.

What Does the Test Involve?

A small blood sample is drawn from a vein, usually in your arm. The blood is then sent to a lab where it is tested for total IgE levels using an immunoassay method. This process typically takes a few days to return results.

What Do My Results Mean?

Results are not provided with specific reference ranges, as they depend on individual health and symptoms. High IgE levels may indicate allergies or other immune conditions, while low levels might suggest a reduced immune response in certain contexts. Always discuss your results with your healthcare provider for interpretation.

What Are Common Causes of Abnormal Results?

Elevated IgE levels can be caused by allergies (e.g., to pollen, dust, or foods), asthma, eczema, parasitic infections, or certain autoimmune diseases. Low IgE levels are less common and may be associated with rare genetic conditions or immune deficiencies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Understanding Your IgE Levels

Short name

IgE Total

Frequently asked questions

How often will I need this test?
The frequency of this test depends on your symptoms and medical history. Your healthcare provider will determine how often you need retests, which could range from once to multiple times a year or as needed for monitoring treatment responses.
Can IgE levels change over time?
Yes, IgE levels can fluctuate based on exposure to allergens, underlying health conditions, and treatments. For example, reducing exposure to allergens or taking allergy medications may lower IgE levels over time.
Is there anything I should avoid before the test?
Generally, no special preparations are needed for this blood test. However, if you are on certain medications (like steroids), inform your healthcare provider before the test, as they may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy