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Immunodeficiency Panel with Specific Antibody Screening (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for certain antibodies that may indicate an immune system deficiency, helping identify potential causes of recurrent infections or weakened immunity.

Quick summary

["This screening helps determine if your immune system may be missing key protective proteins."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45268-0
Short code
Immunodeficiency Pnl Bld FC
Synonyms
Immunodeficiency Pnl Bld FC
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test evaluates the presence of specific antibodies in your blood that are linked to common immunodeficiency conditions. These antibodies may be absent or reduced in people with certain genetic or acquired immune deficiencies. Results can help guide further testing or treatment plans.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have frequent or severe infections that don’t respond to typical treatments, or if you have a family history of immunodeficiency. It may also be used in newborn screening or before certain medical procedures.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The blood is processed to separate serum or plasma, which is then tested for specific antibody levels. This process is quick and typically done in a lab setting.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to avoid certain medications or foods for a short time if instructed by your provider. Always inform your healthcare team about any medications or supplements you’re taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Immunodeficiency Antibody Screen

Frequently asked questions

What does a positive or abnormal result mean?
An abnormal result may indicate a deficiency in certain immune components, which your doctor will discuss with you. This could mean you need additional testing or a referral to a specialist for further evaluation.
How long will it take to get results?
Results are typically available within 1 to 3 business days, depending on lab processing times. Your healthcare provider will contact you with the findings once they are ready.
Can I fast before this test?
No fasting is required for this test, but always follow your healthcare provider’s specific instructions if they provide any.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy