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Indirect Platelet-Associated IgG, Serum/Plasma — Qualitative, Flow Cytometry

Published: August 9, 2026Updated: August 16, 2026

Detects IgG in serum or plasma that binds to platelets using flow cytometry, helping evaluate suspected platelet antibodies.

Quick summary

["A positive result suggests circulating IgG antibodies that can bind to platelets, but it must be interpreted with your clinical findings."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73333-7
Short code
IMP+CS ind plt IgG SerPl Ql FC
Synonyms
IMP+CS ind plt IgG SerPl Ql FC
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This indirect flow-cytometry test looks for IgG in serum or plasma that binds to platelets. It is used to help evaluate whether circulating antibodies may be affecting platelet function or platelet counts.

Why might I need this test?

A clinician may order this test when unexplained low platelet counts, bleeding, or a history of a transfusion or pregnancy reaction raises concern for platelet antibodies. It can also help investigate certain immune or alloimmune platelet disorders.

How is the test performed?

A blood sample is collected, separated into serum or plasma, and mixed with test platelets. Flow cytometry then measures whether the patient's sample contains IgG that binds to those platelets.

How do I prepare for the test?

No special preparation or fasting is usually required. Tell your clinician if you recently received a blood or platelet transfusion, because donor antibodies may affect the results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Indirect platelet-associated IgG

Frequently asked questions

Does a positive result mean I definitely have a platelet disorder?
No. It shows that platelet-binding IgG was detected, but your clinician must interpret it with your symptoms, platelet count, medical history, and other tests.
Is this the same as testing IgG already attached to my platelets?
No. This is an indirect test, meaning the laboratory tests your serum or plasma against test platelets rather than measuring IgG directly on your own platelets.
Can recent transfusions affect the result?
Yes. Antibodies or IgG from recently transfused blood products can sometimes influence an indirect platelet-antibody test, so the laboratory should be told about recent transfusions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy