Serum/plasma mass concentration of albumin (total protein-related, protein electrophoresis)
This test measures the total protein content in your blood, broken down into specific protein fractions, including albumin. Albumin is a key protein that helps maintain fluid balance and supports immune function.
["Albumin and protein fractions help assess kidney function, nutritional status, and overall protein balance in your blood."]
Key facts at a glance
- LOINC
- 47316-5
- Short code
- Inner ear 68kD Ab SerPl IA-aCnc
- Synonyms
- Inner ear 68kD Ab SerPl IA-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Albumin and Protein Fractions Matter
Albumin is one of the most abundant proteins in your blood and plays a critical role in keeping fluids where they need to be (like in your blood vessels) rather than leaking into tissues. Low albumin levels can signal problems like kidney disease, malnutrition, or liver issues. The other protein fractions (like globulins) help fight infections and transport substances like hormones and vitamins. Together, these measurements give doctors insight into how well your body is producing and balancing proteins.
How This Test Works
This test uses a technique called electrophoresis to separate different protein types in your blood sample. The sample is placed in an electric field, causing proteins to move at different speeds based on their size and charge. The result is a graph showing the distribution of these proteins, including albumin and other fractions. This helps identify any imbalances that might need further investigation.
What the Results Could Indicate
If your albumin levels are too low, it might mean your body isn’t making enough albumin, which could be due to liver disease, kidney problems, or poor nutrition. High levels of certain globulins might suggest chronic infections, inflammation, or autoimmune conditions. Doctors use these results to guide treatment plans, especially for conditions like kidney disease, liver disorders, or immune-related illnesses.
Common Conditions Monitored
Doctors often check albumin and protein fractions in people with kidney disease, liver problems, malnutrition, or chronic infections. These tests can also help monitor how well treatments are working for conditions like cirrhosis, nephrotic syndrome, or certain cancers.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Albumin Profile (Serum/Plasma)
Frequently asked questions
What does a low or high protein fraction mean for my health?
How often should I get this test?
Can I prepare for this test differently based on the protein fractions being checked?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy