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C-reactive protein (CRP) concentration in serum/plasma

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps doctors identify and monitor inflammation, often used to check for infections, autoimmune conditions, or other health concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
111874-4
Short code
Insertion time Endscpy
Synonyms
Insertion time Endscpy
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
endoscopy
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why CRP Testing Matters

CRP is a marker that rises when your body is fighting inflammation. It can appear in blood tests to help diagnose conditions like infections, heart disease, or inflammatory diseases such as rheumatoid arthritis. CRP levels can also be checked after surgery or during recovery to ensure inflammation is under control.

What to Expect Before the Test

No special preparation is usually needed for this test. You may be asked to fast for 8–12 hours before the draw if your lab uses a specific method for CRP measurement. Your doctor or lab technician will explain any instructions if needed. The test is typically done by drawing blood from a vein in your arm.

What the Results Mean

CRP results are often reported in milligrams per liter (mg/L). Higher levels may indicate inflammation, infections, or other health issues. Your doctor will interpret the results in the context of your overall health and medical history.

Common Conditions Monitored

CRP is commonly used to monitor conditions like infections (e.g., pneumonia, urinary tract infections), autoimmune diseases (e.g., lupus, rheumatoid arthritis), and to assess risk for heart disease. It can also help track how well treatment is working for these conditions.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated CRP levels can signal an active inflammatory process, guiding treatment decisions for infections, autoimmune disorders, or post-surgical monitoring. While CRP is not specific to any single condition, it provides a broad measure of systemic inflammation that can prompt further investigation or adjustments to care plans.

Short name

CRP (Serum/Plasma)

Frequently asked questions

What causes CRP levels to change?
CRP levels can rise due to infections (like colds or flu), injuries, surgeries, or certain medications. They may also be higher in people with chronic conditions like heart disease or autoimmune disorders. Stress, smoking, or obesity can sometimes influence CRP levels, though they are not the primary cause.
How often should CRP be checked?
Your doctor will determine how often to check CRP based on your health needs. Some people may need CRP tests regularly if they have conditions like heart disease or autoimmune disorders. Others may only need it if symptoms suggest inflammation is present.
Can CRP levels be affected by diet or exercise?
Yes, lifestyle factors like diet and exercise can influence CRP levels. Eating a heart-healthy diet, staying active, and maintaining a healthy weight may help lower CRP levels. However, CRP is primarily a marker of inflammation, so diet and exercise are not the only factors considered in interpreting results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy