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Serum Insulin with 15-Minute Postprandial Glucose Measurement (Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test measures your insulin levels after eating a meal, along with your blood sugar response 15 minutes later. It helps assess how your body responds to glucose and may be used in diabetes management.

Quick summary

["This test helps evaluate how well your body regulates blood sugar after eating."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55499-8
Short code
Insulin 15M p Glc IV SerPl-sCnc
Synonyms
Insulin 15M p Glc IV SerPl-sCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test includes two key measurements: your insulin concentration in serum and your blood glucose level taken 15 minutes post-meal. Insulin is a hormone that helps control blood sugar levels. The combination of these two values can provide insight into how efficiently your pancreas releases insulin in response to food intake.

Why It’s Done

Doctors may order this test to diagnose or monitor conditions like diabetes, particularly Type 1 or Type 2 diabetes, or to evaluate how well a person’s current treatment plan is working. It can also help identify issues with insulin sensitivity or pancreatic function.

How It’s Performed

You’ll fast for a specified period before the test, typically overnight. A blood sample is drawn from a vein, usually in your arm, to measure insulin levels. After eating a meal, a second blood sample is taken 15 minutes later to check your blood sugar response.

Preparation and Timing

Fasting is required before the initial blood draw. Follow your healthcare provider’s instructions regarding when to eat or drink. The timing of the second blood draw depends on your meal, so plan accordingly to ensure accurate results.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is particularly useful for diagnosing or managing diabetes by assessing how your body responds to glucose. Abnormal results may indicate impaired insulin secretion, resistance, or other metabolic issues. It can also help identify prediabetes or help tailor treatment plans, such as medication adjustments or lifestyle changes.

Frequently asked questions

How long does it take to get results from this test?
Results from this test are typically available within a few days to a week, depending on your laboratory and healthcare provider. Follow-up appointments may be scheduled based on your results.
What does a high or low insulin level mean in this test?
High insulin levels combined with elevated blood sugar after eating may suggest insulin resistance or other metabolic disorders. Low insulin levels could indicate issues with insulin production or function, which may require further evaluation by a healthcare provider.
Can I eat or drink anything before the second blood draw?
No, you should not eat or drink anything except water before the second blood draw, as it must be taken 15 minutes after consuming your meal to accurately measure your postprandial response.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy