Serum Insulin with 24-Hour Glucose Profile (High-Pressure Liquid Chromatography)

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of diabetes, insulin resistance, or unexplained weight changes. It may also be used to monitor conditions like prediabetes, gestational diabetes, or to evaluate metabolic disorders affecting insulin and glucose balance.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to fast for a certain period before the blood draw. Follow your provider’s instructions carefully. If you are taking medications that affect glucose or insulin levels, inform your healthcare team beforehand.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. The blood sample will be processed to separate serum and analyzed for insulin levels. Glucose monitoring may involve additional measurements over time or in specific conditions (e.g., postprandial).

What the Results Mean

Insulin levels alone can indicate whether your pancreas produces enough insulin, but combining them with glucose data provides a clearer picture of how your body manages energy. Abnormal results may suggest diabetes, metabolic syndrome, or other endocrine issues.