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Insulin with 24-Hour Average Glucose Profile (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures your insulin levels alongside a 24-hour average of your blood glucose to help assess how your body manages glucose over time, particularly useful in diabetes monitoring.

Quick summary

["Helps track how insulin and glucose interact in your body over a full day."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47666-3
Short code
Insulin 5M pre Glc SerPl-aCnc
Synonyms
Insulin 5M pre Glc SerPl-aCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have diabetes, prediabetes, or if you’re experiencing symptoms like frequent urination, extreme thirst, or unexplained weight changes. It can also help evaluate how well your current diabetes treatment is working or if you’re at risk for complications like hypoglycemia or hyperglycemia.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to fast for a short period before your blood is drawn. If you’re taking certain medications, let your provider know. Your blood sample will be taken from a vein in your arm.

What the Test Results Mean

Insulin levels alone don’t give a full picture of glucose control. This test combines insulin data with your average blood glucose over 24 hours to provide a clearer picture of how your body’s hormones and glucose levels interact daily. Results may be used to adjust treatment plans, such as insulin dosages or lifestyle changes.

How the Test Works

Blood is drawn to measure insulin concentration in your serum or plasma. Simultaneously, glucose levels are tracked over 24 hours using continuous glucose monitoring or periodic blood tests, and averaged to create a profile. This helps identify patterns in glucose fluctuations that may not be obvious from single measurements.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How does this test help diagnose or manage diabetes?
This test helps assess how effectively your body regulates blood sugar by evaluating insulin production and glucose metabolism over time. It can reveal whether you’re consistently at risk for high or low blood sugar, guiding treatment decisions to improve long-term health outcomes.
What if my insulin levels are high or low?
High insulin levels might indicate insulin resistance, overproduction of insulin, or other metabolic issues. Low insulin levels could suggest diabetes, pancreatic problems, or inadequate treatment. Your provider will interpret results in the context of your symptoms, other tests, and medical history to determine the best next steps.
Can I eat or drink before this test?
Most often, no fasting is required, but follow your provider’s instructions. If you’re unsure, ask whether to avoid food/drink for a short period before your blood draw. Some tests may require fasting for accuracy, so confirm with your healthcare team.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy