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Serum Insulin Concentration (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of insulin in your blood serum, a hormone produced by the pancreas that helps regulate blood sugar levels.

Quick summary

["Insulin levels help assess your body’s ability to manage glucose and identify potential diabetes or metabolic issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55390-9
Short code
Insulin 6h p chal SerPl-sCnc
Synonyms
Insulin 6h p chal SerPl-sCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for diabetes, insulin resistance, or other conditions affecting blood sugar control, such as hypoglycemia or pancreatic disorders. It can also be used to monitor treatment progress for conditions like prediabetes or type 1 or 2 diabetes.

Your blood sample is drawn from a vein, usually in your arm, and sent to a lab for analysis. Serum (the liquid part after clotting) is used for this test.

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a glucose tolerance or fasting profile.

Results are interpreted by your healthcare provider based on your overall health, symptoms, and test context. Abnormal levels may signal diabetes, insulin resistance, or other metabolic conditions.

High insulin levels might indicate insulin resistance, pancreatic tumors, or other endocrine disorders. Low levels could suggest diabetes, starvation, or certain medications affecting insulin production.

Factors like diet, stress, medications (e.g., steroids, diabetes drugs), or underlying conditions (e.g., pancreatitis, liver disease) can influence insulin levels. Your doctor will review these factors with your results.

This test is often part of a broader evaluation for blood sugar management, especially if you have symptoms like excessive thirst, fatigue, or unexplained weight changes.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

What if I Have Diabetes and My Insulin Level Is High?
Elevated insulin in diabetes may indicate insulin resistance, where your body doesn’t respond well to insulin. Your doctor may recommend lifestyle changes, medications, or further testing to manage this.
If fasting is required (e.g., for a fasting insulin test), avoid food or drink except water for 8–12 hours beforehand. Ask your doctor or lab for exact instructions.
Yes. Insulin measures hormone levels, while glucose tests measure blood sugar directly. Both are used together to assess metabolic health, but they serve different purposes.
How Often Should I Get This Test?
Frequency depends on your health status. People with diabetes may need regular testing (e.g., every 3–6 months), while others may only need it if symptoms arise or during evaluations for metabolic disorders.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy