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Insulin, mass concentration in serum (24-hour profile)

Published: August 9, 2026Updated: August 16, 2026

This test measures insulin levels over a 24-hour period in your blood serum to help assess how your body responds to glucose.

Quick summary

["Understanding your insulin levels over time can help diagnose or monitor conditions like diabetes or insulin resistance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47667-1
Short code
Insulin 6M p Gc SerPl-aCnc
Synonyms
Insulin 6M p Gc SerPl-aCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of diabetes, such as frequent urination, excessive thirst, or unexplained weight changes. It may also be used to evaluate how well your body produces insulin or to check for insulin resistance. Some people with prediabetes or suspected insulin-related disorders also get this test.

What to Expect Before the Test

You’ll typically fast for 8 to 12 hours before the test. Your blood will be drawn from a vein in your arm at scheduled intervals over 24 hours. A healthcare professional will explain the process and provide instructions to ensure accuracy.

What the Test Results Mean

The results show insulin levels at different times during the day. Abnormal patterns may indicate issues like insulin deficiency, insulin resistance, or other metabolic conditions. Your provider will interpret the results in relation to your symptoms and medical history.

Common Conditions Linked to This Test

This test helps diagnose or manage diabetes (including type 1 and type 2), insulinoma (a rare tumor that causes excessive insulin production), or conditions affecting insulin sensitivity. It may also be used in research or specialized clinical settings to study glucose metabolism.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

How long does it take to get my insulin 24-hour profile results?
Results are usually available within 1 to 2 weeks, depending on lab processing times and follow-up with your healthcare provider. Your provider will contact you once they have the final report.
Can I eat or drink anything before the blood draws during the 24-hour test?
You must fast (no food or liquids, except water) for 8 to 12 hours before the first draw. After that, you can eat and drink normally, but avoid caffeine or sugary drinks during the test period.
Will the blood draws hurt?
Most people experience only mild discomfort during blood draws. A healthcare professional will apply a small amount of numbing cream if needed, and you may feel a quick pinch. The process is quick, and most people tolerate it well.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy