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Serum Insulin Binding Protein Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of insulin-binding protein in your blood serum. These proteins help regulate how insulin interacts with cells, playing a role in glucose metabolism.

Quick summary

["Understanding your insulin-binding protein levels can help assess how your body processes insulin and supports blood sugar control."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34156-0
Short code
Insulin Bnd SerPl-aCnc
Synonyms
Insulin Bnd SerPl-aCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms related to insulin resistance, metabolic disorders, or conditions affecting protein function. It could also be part of a broader evaluation for diabetes management or research into insulin-related mechanisms.

What to Expect Before the Test

No special preparation is typically needed. You may have a blood draw from a vein in your arm, similar to other routine blood tests. If you’re on certain medications or have a history of bleeding disorders, let your provider know.

What the Results Mean

Results are interpreted in the context of your overall health, symptoms, and medical history. Abnormal levels may suggest issues with insulin binding or metabolism, but further testing or clinical correlation is needed for diagnosis.

Common Conditions Linked to Insulin-Binding Protein Levels

Changes in insulin-binding protein levels can be associated with metabolic syndrome, type 2 diabetes, or conditions affecting protein synthesis or degradation. However, this test alone doesn’t diagnose specific diseases but may guide further investigation.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Insulin Binding Protein Level

Frequently asked questions

How often will I need this test?
The frequency depends on your healthcare provider’s recommendations. Some patients may need it periodically to monitor metabolic health, especially if they have diabetes or related conditions. Follow-up may be based on symptoms, lab trends, or treatment adjustments.
Can diet or exercise affect this test?
Diet and exercise can influence blood sugar and protein levels indirectly. For example, certain diets may impact insulin sensitivity, which could affect how insulin-binding proteins function. However, this test specifically measures protein concentration, so results may not reflect acute dietary changes directly. Always discuss lifestyle factors with your provider.
What if my results are outside the expected range?
If your results are outside the expected range, your provider will review them with you and may order additional tests or consult with a specialist. Abnormal levels could signal underlying issues, but they don’t always indicate a diagnosis on their own. Follow-up will depend on your clinical picture.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy