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Insulin, Serum/Plasma — Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures insulin in serum or plasma to help evaluate blood sugar control, diagnose diabetes, and investigate unexplained low blood sugar.

Quick summary

["An insulin blood test helps clinicians assess how the body regulates blood sugar."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14293-5
Short code
Insulin BS SerPl-sCnc
Synonyms
Insulin BS SerPl-sCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test measures the amount of insulin, a hormone made by the pancreas, in serum or plasma. Insulin helps glucose enter cells for energy and helps keep blood sugar within a healthy range.

Why might I need this test?

Your clinician may order this test when evaluating diabetes, insulin resistance, unexplained low blood sugar, or symptoms that can occur with abnormal insulin levels. It may also be used to monitor certain diabetes treatments.

How is the test performed?

A blood sample is collected, usually by venipuncture, and the insulin level is measured in the laboratory using an immunoassay-based method. The sample is then analyzed as a serum or plasma substance concentration.

How do I prepare for the test?

This test is often performed while fasting, so follow your clinician's instructions about eating and drinking beforehand. Tell your clinician about insulin injections, diabetes medicines, supplements, recent illness, and any symptoms of low blood sugar.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An insulin level that is higher than expected may occur with insulin resistance, obesity, or type 2 diabetes, especially when interpreted alongside glucose and other tests. A lower-than-expected level, particularly with low blood sugar, may suggest inadequate insulin production or excess insulin effect. Results depend on fasting status, timing, medications, and the laboratory's reference interval, so they should be interpreted by a clinician.

Short name

Insulin

Frequently asked questions

Do I need to fast before this test?
Fasting is commonly required, but instructions vary. Follow the specific instructions provided by your clinician or laboratory.
Is this the same as a home blood glucose test?
No. A home glucose meter measures the amount of sugar in blood at that moment, while this laboratory test measures the amount of insulin.
Can I take my diabetes medicines before the test?
Do not stop or change medicines unless your clinician instructs you to. Tell the care team which insulin or diabetes medicines you use and when they were last taken.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy