Insulin IgG Antibody, Serum — Arbitrary Concentration
Measures insulin-specific IgG antibodies in your blood. It may help evaluate certain allergic or autoimmune reactions related to insulin.
["Detecting insulin-specific IgG can support an evaluation for an immune-mediated reaction to insulin."]
Key facts at a glance
- LOINC
- 56533-3
- Short code
- Insulin IgG Ser-aCnc
- Synonyms
- Insulin IgG Ser-aCnc
- Category
- hormone
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 2.6
- Ref high
- 24.9
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 83525
- SNOMED
- 413618004
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This blood test measures IgG antibodies directed against insulin. These antibodies are part of the immune system and may be present after exposure to injected insulin.
Why might I need this test?
A clinician may order this test when allergic-type symptoms, such as itching, rash, swelling, wheezing, or low blood sugar, occur after insulin treatment. It may also be considered when the cause of recurrent low blood sugar is unclear.
How is the test performed?
A blood sample is collected and analyzed in a laboratory using an immunoassay, which detects insulin-specific IgG. The result is reported as an arbitrary concentration because it is not measured in the same units as standard insulin tests.
How do I prepare for the test?
Fasting is usually not required, but follow any instructions from your clinician. Tell the laboratory if you recently received insulin or are taking insulin, because this can affect how the result is interpreted.
Reference range
Fasting: 2.6-24.9 μIU/mLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Detectable insulin-specific IgG may reflect previous immune exposure to insulin and does not by itself prove an allergy or disease. When interpreted with symptoms, insulin-use history, and other laboratory findings, it can help evaluate immune-mediated insulin allergy or, less commonly, insulin autoimmune syndrome.
Short name
Insulin IgG Antibody
Frequently asked questions
Does a positive insulin IgG result mean I am allergic to insulin?
Does this test measure my insulin level?
Can I take my insulin before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy