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Insulin, Fasting — Serum/Plasma, Substance Concentration

Published: August 9, 2026Updated: August 17, 2026

Measures insulin in a fasting blood sample to help evaluate insulin production, insulin resistance, and unexplained changes in blood glucose.

Quick summary

["Fasting insulin shows how much insulin your body is producing at rest and is most useful when interpreted with a glucose level."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
59179-2
Short code
Insulin p fast SerPl-sCnc
Synonyms
Insulin p fast SerPl-sCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

A fasting insulin test measures the amount of insulin in a blood sample drawn after you have not eaten. Insulin is a hormone made by the pancreas that helps glucose enter cells for energy.

Why might I need this test?

Your clinician may order this test to investigate insulin resistance, diabetes risk, unusual blood glucose results, or symptoms of low blood glucose. It is usually interpreted together with a simultaneous fasting glucose test and your medical history.

How is the test performed?

A blood sample is collected and the insulin level is measured in the serum or plasma portion of the sample. The laboratory commonly uses an immunoassay, although the exact method may vary.

How do I prepare for the test?

Follow your clinician's fasting instructions and do not eat or drink anything except water for the specified period. Taking medicines, supplements, or eating can affect the result, so tell the healthcare team about anything that may have influenced the test.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher-than-expected fasting insulin level, especially when glucose is also elevated, may suggest that the body is resisting insulin's effects. A low insulin level can occur with excess insulin production, certain medicines, or pancreatic conditions, but one result alone does not establish a diagnosis. Insulin levels must be interpreted with glucose results, symptoms, medications, and other clinical findings.

Short name

Fasting Insulin

Frequently asked questions

Is fasting insulin the same as an insulin tolerance test?
No. A fasting insulin test is a simple blood measurement taken after a period without food. An insulin tolerance test is a different, monitored procedure used to assess how the body responds to a controlled insulin dose.
Why is my insulin result checked with glucose?
Insulin and glucose show related but different aspects of blood sugar regulation. The combination helps clinicians assess insulin production, insulin resistance, and possible causes of high or low glucose.
Can medicines or illness affect the result?
Yes. Insulin, diabetes medicines, other medicines, recent illness, stress, and food intake can alter insulin levels. Tell your clinician about these factors when the test is ordered.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy