Skip to content

Porcine Insulin Antibody Titer, Serum

Published: August 9, 2026Updated: August 16, 2026

A blood test that measures antibodies against pig-derived (porcine) insulin, which may help evaluate suspected insulin allergy or immune-related insulin resistance.

Quick summary

["This test detects and estimates the level of antibodies directed against porcine insulin in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38490-9
Short code
Insulin Porcine Ab Titr Ser
Synonyms
Insulin Porcine Ab Titr Ser
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test measures the titer, or relative amount, of antibodies your immune system has formed against porcine insulin. Porcine insulin is insulin originally obtained from pigs and may be used when human insulin is not suitable or available.

Why might I need this test?

The test may be ordered if you have had an allergic reaction after receiving insulin or if insulin is not controlling your blood glucose as expected. It can help determine whether an immune response to porcine insulin may be contributing to your symptoms.

How is the test performed?

A blood sample is drawn and tested in a laboratory to detect and estimate the level of porcine insulin antibodies. The result is reported as a titer, which is a measure of antibody concentration rather than a standard blood glucose or insulin level.

How do I prepare for the test?

No special preparation is usually required for this test. If you are taking insulin, do not stop or change it unless your healthcare professional instructs you to do so. Follow any fasting or timing instructions provided by the laboratory or ordering clinician.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A detectable titer shows that antibodies against porcine insulin are present. A significant level may support a diagnosis of an immune reaction to porcine insulin, particularly in someone with allergic symptoms or poor response to insulin therapy. The result must be interpreted with your insulin type, symptoms, treatment history, and other laboratory findings because low levels may not cause symptoms.

Short name

Porcine insulin antibody titer

Frequently asked questions

Does this test measure my usual insulin level?
No. It measures antibodies against porcine insulin, not the amount of insulin circulating in the blood. An insulin level test is a different blood test.
What is porcine insulin?
Porcine insulin is insulin manufactured from pig insulin. It is not the same as a test that checks whether you have antibodies against human insulin.
What symptoms might lead to this test?
It may be considered for allergic-type symptoms after an insulin injection, such as rash, itching, swelling, or difficulty breathing, and in selected cases of unexplained insulin resistance. Your clinician will decide whether the test is appropriate based on your history and examination.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy