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Porcine Insulin-Specific IgE, Total

Published: August 9, 2026Updated: August 16, 2026

Measures total IgE antibodies directed against porcine (pig) insulin to help evaluate a possible immediate allergic reaction to animal-derived insulin.

Quick summary

["Detectable porcine insulin-specific IgE indicates sensitization to porcine insulin and may support a diagnosis of insulin allergy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61276-2
Short code
Insulin Porcine IgE/IgE total %
Synonyms
Insulin Porcine IgE/IgE total %
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test measures IgE antibodies directed against porcine, or pig-derived, insulin. It helps determine whether an immediate allergic reaction to porcine insulin may be immune-mediated.

Why might I need this test?

Your clinician may order this test if you developed hives, wheezing, swelling, or another sudden allergic-type reaction after receiving porcine insulin. It may also be used when evaluating reactions to animal-derived insulin products.

How is the test performed?

A blood sample is collected and tested in a laboratory for antibodies specific to porcine insulin. The result is reported as a measured antibody level or according to the laboratory's testing method.

How do I prepare for the test?

This test usually does not require fasting. Tell your clinician about any insulin products you have used, recent allergic symptoms, and other allergies, because this information may affect interpretation.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Detectable porcine insulin-specific IgE indicates immune sensitization to porcine insulin and, together with a compatible clinical history, may support insulin allergy. An undetectable result makes an IgE-mediated reaction less likely but does not completely exclude allergy. Results should be interpreted by a clinician because antibody levels alone do not prove that a specific reaction will occur.

Short name

Porcine insulin IgE

Frequently asked questions

Does this test show whether I am allergic to human insulin?
No. This test measures antibodies directed specifically against porcine insulin. Other insulin-specific antibody tests may be needed to evaluate a reaction to human insulin.
What symptoms can suggest an insulin allergy?
Possible immediate symptoms include hives, itching, facial or throat swelling, wheezing, shortness of breath, dizziness, or low blood pressure. Severe symptoms require urgent medical attention.
Can I continue my insulin while awaiting the result?
Do not stop prescribed insulin without medical guidance, especially if you use it to prevent dangerously high blood sugar. If you have had a severe allergic reaction, contact your clinician or emergency services promptly.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy