Porcine Insulin-Specific IgG4 Antibodies, Mass Concentration
Measures IgG4 antibodies directed against porcine (pig-derived) insulin in a laboratory specimen.
["This test can document an immune response to porcine insulin, but results must be interpreted with your insulin history and symptoms."]
Key facts at a glance
- LOINC
- 56363-5
- Short code
- Insulin Porcine IgG4-mCnc
- Synonyms
- Insulin Porcine IgG4-mCnc
- Category
- hormone
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 2.6
- Ref high
- 24.9
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 83525
- SNOMED
- 413618004
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This test measures the concentration of IgG4 antibodies that recognize porcine insulin, an insulin made from pigs. It is different from a test that measures the amount of insulin itself.
Why might I need this test?
Your clinician may order this test if you have received porcine insulin or another animal-derived insulin product. The result may help evaluate an anti-insulin antibody response, which can sometimes complicate insulin measurements or blood glucose management.
How is the test performed?
A laboratory sample is analyzed with an immunoassay designed to detect insulin-specific IgG4. The result is reported as a mass concentration, and the exact method may vary by laboratory.
How do I prepare for the test?
No special preparation is usually required unless your clinician or laboratory gives different instructions. Tell your clinician about all insulin products you have used or are currently using, and do not stop insulin unless instructed.
Reference range
Fasting: 2.6-24.9 μIU/mLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A detectable or elevated result indicates an IgG4 immune response to porcine insulin, commonly following exposure to an animal-derived insulin product. This may be relevant when evaluating insulin resistance, unexplained blood glucose patterns, or possible interference with insulin assays. Results should be interpreted with your insulin history, symptoms, and other antibody tests because IgG4 antibodies do not by themselves establish an allergy or explain all abnormal glucose results.
Short name
Porcine insulin IgG4 antibodies
Frequently asked questions
Does this test measure insulin itself?
Why would my clinician test for porcine insulin antibodies?
Does a positive result mean I am allergic to insulin?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy