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Insulin Receptor Antibody (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies that may be present in your blood if your immune system mistakenly attacks insulin receptors, which could affect how your body responds to insulin.

Quick summary

["This test helps diagnose conditions like autoimmune diabetes or other rare disorders linked to insulin receptor antibodies."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13632-5
Short code
Insulin Recep Ab Titr Ser
Synonyms
Insulin Recep Ab Titr Ser
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like unexplained diabetes onset, insulin resistance, or other autoimmune-related symptoms, especially if other tests (like those for type 1 diabetes) have not explained your condition.

How the Test Works

Blood is drawn from a vein in your arm. The sample is tested using an immunoassay method to detect the presence of antibodies that bind to insulin receptors.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if instructed by your provider.

What to Expect During the Test

You’ll lie down comfortably while a healthcare professional inserts a needle into your arm to draw blood. The process takes a few minutes, and you may feel a slight pinch.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results for insulin receptor antibodies can indicate autoimmune diabetes or rare conditions like LADA (latent autoimmune diabetes in adults), where the immune system attacks insulin receptors before or alongside insulin-producing cells. This can sometimes mimic or complicate diabetes management.

Short name

Insulin receptor antibody

Frequently asked questions

What does a positive result mean?
A positive result suggests your immune system may be attacking insulin receptors, which could interfere with insulin function. This may require further evaluation, including monitoring blood sugar levels and possibly adjusting treatment plans.
Can this test be used to diagnose diabetes?
No, this test alone is not used to diagnose diabetes. It’s often ordered alongside other tests (like fasting glucose or HbA1c) to help identify underlying causes of insulin resistance or autoimmune-related diabetes.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your provider will discuss the findings with you.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy