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Insulin Resistance Score, Serum — Cardio IQ Calculated Value

Published: August 9, 2026Updated: August 16, 2026

A calculated estimate of insulin sensitivity based on serum insulin and glucose values. A higher score generally indicates greater insulin resistance.

Quick summary

["This calculated score helps estimate how effectively the body responds to insulin."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92845-7
Short code
Insulin resist score Ser Calc.CardioIQ
Synonyms
Insulin resist score Ser Calc.CardioIQ
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
calculated-cardioiq
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is a calculated blood test result that estimates insulin resistance, meaning how difficult it is for the body to use insulin to regulate blood glucose. It is generally derived from fasting serum insulin and glucose measurements and may also be known as the HOMA-IR score.

Why might I need this test?

A clinician may order this calculation when assessing insulin sensitivity, blood sugar control, metabolic syndrome, type 2 diabetes risk, or cardiovascular risk. It may also be used alongside other tests when evaluating weight changes or conditions such as polycystic ovary syndrome.

How is the test performed?

Blood is collected and tested for glucose and insulin. The laboratory then uses those results to calculate the insulin resistance score. The calculation itself requires no additional procedure.

How do I prepare for the test?

Fasting insulin and glucose measurements are usually needed, so follow the laboratory's instructions about fasting and timing. Continue taking medications unless your clinician tells you otherwise, and tell the clinician if you have recently eaten, exercised, or been ill.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher score generally suggests that the body is less sensitive to insulin, which can occur with excess weight, inactivity, diabetes, metabolic syndrome, or other insulin-resistant conditions. A lower score generally indicates greater insulin sensitivity. The result should be interpreted with other measurements, symptoms, medical history, and medications because it does not diagnose diabetes or cardiovascular disease by itself.

Short name

Insulin resistance score

Frequently asked questions

Does a higher insulin resistance score mean my health is worse?
Generally, a higher score indicates more insulin resistance and may be associated with increased metabolic and cardiovascular risk. The clinical meaning depends on your other test results and health history.
Can this test diagnose diabetes?
No. The score estimates insulin sensitivity, while diabetes is diagnosed using glucose measurements and other clinical criteria. Your clinician will interpret the score together with the rest of your evaluation.
Does the result change if I exercise or eat before the test?
Yes. Food intake, physical activity, illness, and stress can affect insulin and glucose measurements, especially when fasting samples are required. Follow the preparation instructions provided by the laboratory.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy