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Insulin and Cholesterol, Serum/Plasma — Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures insulin and cholesterol concentrations in serum or plasma to help assess blood sugar regulation and cardiovascular risk.

Quick summary

["This blood test provides information about insulin levels and cholesterol, two factors related to metabolic and heart health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33811-1
Short code
Insulin sp12 p chal SerPl-aCnc
Synonyms
Insulin sp12 p chal SerPl-aCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of insulin and cholesterol in a blood sample. Insulin helps regulate blood sugar, while cholesterol is a substance used by the body that is also associated with cardiovascular risk.

Why might I need this test?

A clinician may order this test when evaluating diabetes, insulin resistance, metabolic syndrome, or high cholesterol. The results may also help guide nutrition, exercise, and medication decisions.

How is the test performed?

A blood sample is collected and analyzed in a laboratory. The sample may be taken from a vein and tested as serum or plasma, depending on the laboratory method.

How do I prepare for the test?

Follow the preparation instructions provided by your clinician or laboratory. If fasting is required, avoid food and drinks other than water for the specified period. Do not change insulin or other medication schedules unless your clinician tells you to do so.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Insulin and cholesterol are interpreted together with other findings, such as blood glucose, medical history, and medication use. Elevated insulin can occur with insulin resistance or metabolic syndrome, while elevated cholesterol may indicate increased cardiovascular risk. Results that are unexpectedly high or low should be reviewed by a healthcare professional because diet, activity, illness, and medications can affect them.

Short name

Insulin and cholesterol

Frequently asked questions

Do I need to fast before this test?
It depends on the laboratory instructions. Fasting is commonly used when cholesterol is measured, and it may also be requested when insulin is being assessed for certain medical reasons.
What does a high insulin result mean?
A high insulin level can occur when the body is resistant to insulin, such as with metabolic syndrome or type 2 diabetes. It must be interpreted alongside glucose results and other clinical information.
Does this test diagnose diabetes or high cholesterol on its own?
No. These measurements can support an assessment, but diagnosis generally requires additional tests and clinical evaluation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy