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Insulin, 2-Hour Postprandial, Serum/Plasma — Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures insulin in a blood sample collected 2 hours after eating to assess how the body responds to a meal and regulates blood glucose.

Quick summary

["This test shows how much insulin your body releases in response to food."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33816-0
Short code
Insulin sp2 p chal SerPl-aCnc
Synonyms
Insulin sp2 p chal SerPl-aCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test measures the concentration of insulin, a hormone made by the pancreas that helps move glucose from the bloodstream into cells. The sample is generally collected 2 hours after a meal.

Why might I need this test?

A postprandial insulin test may be used to evaluate insulin production and the body's response to food. It may be ordered alongside glucose and C-peptide measurements when diabetes, insulin resistance, or unusual insulin levels are being evaluated.

How is the test performed?

A blood sample is drawn from a vein and sent to a laboratory for measurement. The laboratory uses a validated immunoassay or another analytical method to determine the insulin concentration.

How do I prepare for the test?

Follow the timing instructions provided by your healthcare professional. Because this is a postprandial test, eat the meal agreed upon with the clinician and have the sample collected at the specified time, usually 2 hours afterward.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Insulin that remains elevated after eating may occur with insulin resistance, obesity, or type 2 diabetes, although other factors can affect the result. Insulin that is lower than expected in the setting of elevated glucose may suggest inadequate insulin production. Results should be interpreted with the meal conditions, glucose levels, medications, and other test findings.

Short name

2-Hour Postprandial Insulin

Frequently asked questions

Why is the collection time important?
Insulin changes rapidly after eating. Collecting the sample at the correct postprandial time makes the result easier to interpret and compare with related glucose measurements.
Does this test diagnose diabetes by itself?
No. A postprandial insulin result is interpreted with blood glucose, symptoms, medical history, and sometimes C-peptide or other laboratory tests.
Do I need to stop taking my diabetes medicines?
Do not stop or change medicines unless your healthcare professional specifically directs you to do so. Some medicines can affect insulin levels, so tell the clinician about all medications and supplements you use.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy