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Insulin, Serum/Plasma — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

A blood test that measures the amount of insulin, often alongside glucose, to assess how the body regulates blood sugar.

Quick summary

["Insulin results are most useful when interpreted with glucose levels, the reason for testing, and the timing of the blood draw."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12741-5
Short code
Insulin sp4 p chal SerPl-mCnc
Synonyms
Insulin sp4 p chal SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures insulin, a hormone made by the pancreas, in blood. Insulin helps glucose enter cells for energy and helps keep blood glucose within a controlled range.

Why might I need this test?

A clinician may order insulin with a glucose test to evaluate fasting blood sugar, insulin resistance, or how the pancreas responds to a glucose load. It may also be used when unexplained low blood sugar is suspected.

How is the test performed?

A blood sample is collected from a vein and analyzed in the laboratory. If insulin is measured during a glucose tolerance test, blood may be drawn more than once at specified times after glucose is given.

How do I prepare for the test?

Fasting may be required, so follow the preparation instructions provided by the laboratory or clinician. Do not stop diabetes medicines or change their schedule unless your healthcare professional specifically directs you to do so.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Insulin that is higher than expected may occur with insulin resistance, metabolic syndrome, or type 2 diabetes, particularly when glucose is also elevated. Insulin that is lower than expected may reflect reduced pancreatic insulin production, prolonged fasting, or certain medicines. Results should be interpreted together with glucose levels, symptoms, medications, and the timing of the specimen.

Short name

Insulin

Frequently asked questions

Is a fasting insulin test the same as an insulin tolerance test?
No. A fasting insulin test measures insulin in a blood sample after a period without food, while an insulin tolerance test measures the body's response to administered insulin and is mainly used to evaluate low blood sugar.
Why are insulin and glucose often tested together?
The two results provide context for one another. Insulin alone does not show how effectively the body is handling the glucose present at the time of testing.
Do I need to stop taking diabetes medication before the test?
Usually not. Some medicines can affect the result, so tell the clinician about all medicines and supplements. Follow their instructions and do not change prescribed treatment without medical guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy