Skip to content

Insulin, Serum/Plasma — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This blood test measures insulin levels in serum or plasma to help assess insulin production and how the body handles glucose.

Quick summary

["Insulin testing helps clinicians evaluate glucose regulation, insulin resistance, and the body's ability to produce insulin."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12743-1
Short code
Insulin sp6 p chal SerPl-mCnc
Synonyms
Insulin sp6 p chal SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of insulin in a blood sample. Insulin is a hormone made by the pancreas that helps glucose enter cells for energy.

Why might I need this test?

Insulin may be measured when diabetes, prediabetes, insulin resistance, or symptoms related to abnormal blood glucose are being evaluated. It is often interpreted together with a glucose level and may be paired with other tests, such as C-peptide.

How is the test performed?

A blood sample is collected, and the serum or plasma is separated for laboratory measurement. The result reports the insulin concentration in the blood.

How do I prepare for the test?

Fasting may be requested, but preparation depends on the reason for testing and your clinician's instructions. The timing of the test relative to meals and insulin or diabetes medications is important, so do not change or stop prescribed insulin without medical advice.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher insulin level may occur with insulin resistance, type 2 diabetes, or after receiving insulin. A lower level may indicate reduced insulin production. Results must be interpreted with glucose levels, the time of the blood draw, and any relevant medications because food intake and treatment can affect insulin concentration.

Short name

Insulin

Frequently asked questions

Is a fasting blood sample required for insulin testing?
Sometimes, but not always. Your clinician will tell you whether to fast and should specify when the sample should be taken.
Why are insulin and glucose often checked together?
The two results help show how the body is regulating blood glucose. Insulin and glucose together provide more context than either value alone.
Does a high insulin result always mean I have diabetes?
No. Insulin can be elevated because of insulin resistance, food intake, medications, or other conditions, so the result must be interpreted with the rest of your evaluation.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy