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Insulin and Cholesterol, Serum/Plasma — Analyte Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures insulin and a cholesterol-related analyte in serum or plasma to help evaluate metabolism and cardiovascular risk.

Quick summary

["This blood test can provide information about insulin function and cholesterol status."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33819-4
Short code
Insulin sp9 p chal SerPl-aCnc
Synonyms
Insulin sp9 p chal SerPl-aCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures insulin and a cholesterol-related substance in blood. Insulin reflects how the body handles glucose, while cholesterol measurements help assess cardiovascular risk. The exact cholesterol fraction and insulin measurement are determined by the laboratory order.

Why might I need this test?

These measurements may be ordered when evaluating blood sugar control, insulin resistance, metabolic health, or cholesterol-related cardiovascular risk. They may also be used to monitor diabetes, weight-management, or lipid-treatment plans.

How is the test performed?

A healthcare professional draws blood from a vein. The sample may be allowed to clot so that serum is separated, or it may be centrifuged to obtain plasma, depending on the laboratory method. The specimen is then analyzed for insulin and the specified cholesterol-related substance.

How do I prepare for the test?

Follow any fasting or timing instructions provided with your lab order, especially when insulin or lipid results are being compared. Fast for the required period, drink only water if permitted, avoid strenuous exercise beforehand, and tell the healthcare team about medicines or supplements that may affect the results.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated insulin can occur with insulin resistance, metabolic syndrome, polycystic ovary syndrome, or other conditions affecting glucose metabolism, but one result alone does not establish a diagnosis. Abnormal cholesterol results may reflect dyslipidemia and can contribute to cardiovascular risk assessment. Results should be interpreted with symptoms, medical history, other laboratory tests, and the specific type of cholesterol measured.

Short name

Insulin and cholesterol

Frequently asked questions

Does this test require fasting?
It may, depending on the specific insulin and cholesterol measurements ordered. Follow the fasting and timing instructions given by your healthcare provider or laboratory.
What does an abnormal insulin result mean?
An unexpectedly high or low insulin result can reflect changes in glucose metabolism, illness, fasting status, or certain medicines. Your healthcare provider will interpret it alongside glucose and other relevant findings.
Why are cholesterol fractions important?
Total cholesterol and its fractions provide different information about blood lipids and cardiovascular risk. The report identifies the specific cholesterol measurement that was performed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy