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Insulin, Serum/Plasma — Substance Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of insulin in a blood sample to help evaluate blood sugar control, insulin production, and possible insulin resistance.

Quick summary

["This blood test shows how much insulin is present and is interpreted together with your blood glucose and medical history."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25699-0
Short code
Insulin sp9 p chal SerPl-sCnc
Synonyms
Insulin sp9 p chal SerPl-sCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures insulin, a hormone made by the pancreas that helps glucose move from the bloodstream into cells for energy. The result may be reported from a serum or plasma blood sample.

Why might I need this test?

Insulin testing may be used when diabetes, low blood sugar, insulin resistance, or unusual insulin levels are being evaluated. It may also be measured during a glucose tolerance test to see how the body responds to sugar.

How is the test performed?

A healthcare professional draws blood into a tube, and the laboratory measures the insulin concentration in the serum or plasma. If the test is part of a glucose challenge, blood may be collected at specific times before and after you drink a glucose solution.

How do I prepare for the test?

Follow the fasting and timing instructions provided by your clinician. If timed samples are required, remain at the testing location as directed. Do not stop insulin or other diabetes medicines unless your clinician specifically instructs you to do so.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Insulin results must be interpreted with the blood glucose level and the conditions of the test. More insulin than expected may occur with insulin resistance or high blood sugar, while less insulin than expected may suggest reduced insulin production. Unexpectedly high insulin with low blood sugar can sometimes result from injected insulin or an insulin-producing condition and should be evaluated by a clinician.

Short name

Serum/Plasma Insulin

Frequently asked questions

Is this the same as a fasting glucose test?
No. Glucose measures the amount of sugar in the blood, while this test measures the amount of insulin released into the blood. They are often evaluated together.
Does a high insulin result always mean I have diabetes?
No. High insulin can occur with insulin resistance and may be seen before or alongside type 2 diabetes, but other factors can affect the result. Your clinician will interpret it with your glucose levels and medical history.
Why are multiple insulin measurements sometimes needed?
Insulin changes throughout the day and after food or glucose. Timed measurements can show how the pancreas responds to a glucose challenge, which may provide more information than a single result.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy