Intestinal Goblet Cell IgA, Serum, Qualitative
This test looks for a type of antibody (IgA) in the blood that targets intestinal goblet cells. It is used as a supporting marker when evaluating certain autoimmune intestinal conditions.
["A positive result can support the suspicion of an autoimmune intestinal disorder but must be interpreted alongside symptoms, biopsy, and other tests."]
Key facts at a glance
- LOINC
- 107490-5
- Short code
- Intestinal goblet cell IgA Ser Ql IF
- Synonyms
- Intestinal goblet cell IgA Ser Ql IF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects immunoglobulin A antibodies directed against goblet cells, which are the mucus-producing cells lining the intestine. A qualitative result simply reports whether these antibodies appear to be present or absent rather than giving an exact amount.
Why It May Be Ordered
Your clinician may order this test when trying to evaluate chronic diarrhea, unexplained intestinal inflammation, or a suspected autoimmune condition affecting the gut. It is generally used as one piece of a larger diagnostic workup rather than on its own.
How the Sample Is Collected
A standard blood draw from a vein in your arm is used to obtain the serum sample. No special preparation is usually required, though you should follow any specific instructions your laboratory or care team provides.
What Results Can Mean
A positive result suggests these antibodies are present and may point toward an autoimmune intestinal process, but it does not confirm a diagnosis by itself. A negative result makes such a condition less likely but also does not rule it out. Results are always interpreted with your symptoms, imaging, biopsy findings, and other laboratory tests.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Goblet cell IgA antibodies are studied mainly as a marker in autoimmune enteropathy and related conditions in which the immune system targets the intestinal lining. Because these antibodies are not entirely specific, they are most useful when combined with clinical history, endoscopic biopsy, and additional serologic testing. Treatment decisions should never rest on this single result.
Short name
Goblet Cell IgA Antibody
Frequently asked questions
Does a positive result mean I definitely have an intestinal disease?
Do I need to fast before this blood test?
Can medications affect the result?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy