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Plasma Fibrin Degradation Products (FDP) – Quantitative

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of small fragments of fibrin, which form when blood clots dissolve naturally. These fragments can indicate whether your body is actively breaking down clots, a process called fibrinolysis.

Quick summary

["Assessing clot breakdown helps identify bleeding risks or excessive clotting activity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
98125-8
Short code
Intravascular coag + fibrinolysis Pnl
Synonyms
Intravascular coag + fibrinolysis Pnl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like unexplained bruising, bleeding gums, heavy menstrual periods, or signs of clotting disorders. It’s also used to monitor conditions like disseminated intravascular coagulation (DIC) or to check for abnormal clot breakdown after surgery or trauma.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into a vein (usually in your arm) to draw a blood sample. It usually takes a few minutes, and you may feel a brief pinch. Avoid eating or drinking for 2 hours before the test if instructed.

What Happens During the Test

The blood sample is sent to a lab where it’s analyzed to detect fibrin degradation products. The results help determine if your body is breaking down clots at a normal or abnormal rate.

What the Results Mean

High levels of FDP may suggest active fibrinolysis (clot breakdown), which can be seen in conditions like DIC, severe infections, or certain cancers. Low or normal levels typically indicate stable clot formation. Your provider will discuss these results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated FDP levels can signal underlying bleeding risks or complications from clotting disorders. For example, very high levels might indicate DIC, a life-threatening condition where clots and bleeding occur simultaneously. Monitoring FDP helps guide treatment decisions, such as blood transfusions or anticoagulant therapy.

Short name

FDP Level

Frequently asked questions

What causes abnormal FDP levels?
FDP levels can be elevated due to conditions like disseminated intravascular coagulation (DIC), severe infections, trauma, surgery, or certain cancers. They may also rise after a heart attack or stroke. Conversely, low levels might suggest a reduced risk of clot breakdown, but this isn’t always the case without clinical correlation.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing times. Your healthcare provider will contact you once they have the results and explain what they mean for your health.
Can I take anything to lower my FDP levels?
No, there’s no specific medication or supplement to lower FDP levels on its own. However, treating the underlying cause—such as infections, clotting disorders, or trauma—can help stabilize your levels. Follow your provider’s advice for managing any conditions that may affect your test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy