Coagulation Function Profile (Plasma)
This test measures several blood components involved in clotting to assess your body’s ability to form blood clots safely and effectively.
["Helps diagnose bleeding or clotting disorders by checking key clotting factors and function."]
Key facts at a glance
- LOINC
- 72661-2
- Short code
- Intrnsc coag fctr act pnl PPP
- Synonyms
- Intrnsc coag fctr act pnl PPP
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 2
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- coag
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test evaluates multiple clotting factors, including prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen levels, and possibly thrombin time or fibrin degradation products, depending on the lab’s specific panel. These measures help identify abnormalities in blood clotting pathways.
Common Conditions Monitored
This panel is often used to monitor conditions like bleeding disorders (e.g., hemophilia), clotting disorders (e.g., deep vein thrombosis risk), liver disease (which affects clotting factor production), or after treatments like anticoagulants (e.g., warfarin). It may also be used pre- and post-surgery to assess clotting risks.
Sample Collection and Preparation
A blood sample is drawn from a vein, typically in the arm. Plasma is separated from blood cells and used for testing. If you’re on anticoagulant medication, your doctor may adjust timing to ensure accurate results.
When You Might Need This Test
Your doctor may recommend this test if you have symptoms like excessive bleeding, unexplained bruising, prolonged bleeding after cuts, or if you’re at higher risk for clots (e.g., after surgery, heart disease, or long periods of immobility).
Reference range
NCBI: SCC <2.0 ng/mLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Coagulation Panel
Frequently asked questions
Why might my results be abnormal?
How do I prepare for this test?
What do I do if I have a bleeding disorder?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy