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Serum or Plasma *Bromocresol Green Protein Fraction* (Invasion Depth/Trend)

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of specific protein fractions in your blood using the bromocresol green dye-binding method. It helps assess protein distribution and potential abnormalities in protein synthesis or breakdown over time.

Quick summary

["This test provides insights into protein metabolism and may help detect conditions affecting protein balance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111981-7
Short code
Invasion depth Blry tr Endscpy
Synonyms
Invasion depth Blry tr Endscpy
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
endoscopy
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The bromocresol green method evaluates protein fractions by binding to specific proteins in your blood sample. This technique separates and quantifies different protein groups, including albumin and globulins, to identify trends in protein concentration or distribution.

Why It Matters in Your Health

Changes in protein fractions can signal underlying health issues, such as liver disease, kidney problems, malnutrition, or inflammatory conditions. Tracking trends over time helps healthcare providers monitor protein metabolism and adjust treatments accordingly.

How the Test Works

Your blood sample is processed to isolate protein fractions. The bromocresol green dye binds selectively to certain proteins, allowing for separation and measurement of their concentrations. Results are presented as trends or specific depth measurements of protein invasion.

Common Conditions Monitored

This test may be used to evaluate liver function, protein synthesis disorders, or systemic protein abnormalities. It can also help assess response to treatments affecting protein levels, such as those for kidney disease or chronic inflammation.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Protein Fraction Profile

Frequently asked questions

What does an abnormal result mean?
An abnormal result may indicate conditions like liver disease, malnutrition, or protein-losing syndromes. Your healthcare provider will discuss findings in the context of your symptoms and medical history to determine next steps.
How often will I need this test?
Frequency depends on your medical condition and treatment plan. Some patients may need this test periodically to track protein trends, while others may only need it once for diagnostic purposes.
Can diet or medications affect this test?
Yes, certain diets (e.g., high-protein or low-protein), medications (e.g., steroids, chemotherapy), or liver/kidney conditions can influence protein levels. Always inform your healthcare provider about all medications or dietary changes before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy