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Iodine-Free Serum Protein Mass Concentration (or Iodine-Free Protein Profile)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood that has had iodine removed, often used in specialized diagnostic or research settings to assess protein composition.

Quick summary

["This test helps identify protein patterns that may relate to certain medical conditions or research studies."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
18367-3
Short code
Iodine Free SerPl-mCnc
Synonyms
Iodine Free SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test quantifies the mass concentration of proteins in your serum after iodine has been removed. Iodine is sometimes added to proteins for easier detection or separation in lab techniques like electrophoresis. Removing iodine allows for a more precise measurement of protein types and quantities.

Why Might Your Doctor Order This Test?

Your doctor may request this test if they suspect a condition affecting protein structure, such as certain genetic disorders, metabolic issues, or when evaluating protein patterns for research purposes. It may also be used in specialized diagnostic procedures like protein electrophoresis.

How Is the Sample Collected?

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate the serum, which is sent to the lab for analysis. The iodine is chemically removed from the proteins before measurement.

What Can This Test Tell You About Your Health?

This test can provide insights into the overall protein profile in your bloodstream. Abnormal patterns may indicate issues with protein synthesis, breakdown, or specific genetic conditions. It’s particularly useful in diagnosing or monitoring conditions that affect protein metabolism or structural integrity.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Iodine-Free Serum Protein Analysis

Frequently asked questions

How long does it take to get results from this test?
Results from this test typically take several days to a week, depending on the lab’s processing schedule and any additional testing required. Your healthcare provider will contact you once results are available.
What does an abnormal result mean?
An abnormal result may suggest an underlying condition affecting protein metabolism or structure, such as certain genetic disorders, liver or kidney disease, or metabolic syndromes. Your doctor will discuss the results in detail and may recommend further testing or treatment options.
Can I prepare for this test in any special way?
No special preparation is needed for this test. However, avoid taking any medications that might affect protein levels (like certain blood pressure or thyroid medications) and inform your doctor about all medications you’re currently taking before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy