Skip to content

Iodine-free serum/plasma mass concentration (e.g., iodine content in a sample)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of iodine present in your blood, either in serum or plasma. Iodine is essential for thyroid hormone production, which helps regulate metabolism.

Quick summary

["Assessing iodine levels helps ensure your thyroid functions properly and prevents deficiencies or excesses that could impact energy and health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2493-5
Short code
Iodine Free Ur-mCnc
Synonyms
Iodine Free Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like fatigue, weight changes, or thyroid-related issues. It can also be part of routine screening for iodine balance, especially in areas where iodine deficiency is common.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from a vein in your arm. If you’re tested for urine iodine, you may need to collect a 24-hour urine sample.

What the Results Mean

Results help determine if your iodine levels are too low (hypothyroidism risk) or too high (possible thyroid overactivity or medication side effects). Interpretation depends on clinical context and your overall health.

Common Causes and Conditions

Low iodine levels may result from diet low in iodized salt, thyroid disorders, or malabsorption issues. High levels could stem from excessive iodine intake (e.g., supplements, medications) or thyroid overactivity.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Iodine deficiency is a global health concern linked to thyroid dysfunction, goiter, and developmental delays in children. Excess iodine can disrupt thyroid hormone production or cause temporary thyroid dysfunction.

Short name

Iodine Level (Serum/Plasma)

Frequently asked questions

Why might my iodine test be ordered even if I don’t have obvious symptoms?
Your provider may recommend it to check for underlying thyroid issues, monitor thyroid medication effectiveness, or screen for iodine deficiency in areas with limited access to iodized salt.
What should I do if my iodine levels are outside the expected range?
Follow your healthcare provider’s advice—this could involve dietary changes (e.g., eating iodized salt), thyroid medication adjustments, or further testing to identify the cause.
Can dietary supplements or medications affect my iodine test results?
Yes, excessive iodine supplements, contrast dyes, or certain medications (e.g., amiodarone) may raise iodine levels. Avoid taking them before testing unless instructed by your provider.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy