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Angiotensin II (measured via plasma concentration using immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of angiotensin II, a hormone involved in regulating blood pressure and fluid balance in your body.

Quick summary

["Angiotensin II helps control how much blood your heart pumps and the resistance in your blood vessels, affecting your blood pressure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73326-1
Short code
Irbesartan+HTCZ ind plt IgM SerPl Ql FC
Synonyms
Irbesartan+HTCZ ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Angiotensin II?

Angiotensin II is a potent vasoconstrictor, meaning it narrows blood vessels to increase blood pressure. It also stimulates the release of aldosterone, a hormone that helps retain sodium and water in your body, further influencing blood volume and pressure.

Why Might You Need This Test?

Your doctor may order this test to evaluate your response to medications like angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs), which work by blocking angiotensin II’s effects. It can also help assess conditions affecting blood pressure regulation, such as kidney disease or heart failure.

How Is This Test Performed?

A blood sample is taken from a vein, usually in your arm. The blood is then processed to separate plasma, where angiotensin II levels are measured using an immunoassay method, which detects specific proteins in the sample.

What Does the Result Mean?

Results are not typically provided as absolute numbers in this context, as angiotensin II levels vary based on medications, hydration status, and other factors. Your doctor will interpret the result in relation to your medical history and treatment goals.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High levels of angiotensin II may indicate poor control of blood pressure or resistance to medications designed to block its effects. Low levels could suggest over-treatment with ACE inhibitors or ARBs, but this is less common. Monitoring angiotensin II helps optimize therapy for conditions like hypertension or heart disease.

Short name

Angiotensin II Level

Frequently asked questions

What does a high angiotensin II level mean?
A high level may suggest your body is still producing significant amounts of angiotensin II, which could indicate ineffective blood pressure management or underlying conditions like kidney dysfunction. Your doctor will discuss this with you in the context of your treatment plan.
How does angiotensin II relate to my blood pressure medications?
Angiotensin II is the target of many blood pressure medications. If your levels are high, your doctor may adjust your dose or consider alternative medications to better control your blood pressure.
Can diet or lifestyle changes affect angiotensin II levels?
Yes, factors like sodium intake, hydration status, and certain medications can influence angiotensin II levels. Reducing salt, managing stress, and maintaining a healthy weight may indirectly support better blood pressure control, but this test alone doesn’t measure those effects directly.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy