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Ferric Ferrocyanide Complex in Serum (Iron Binding Capacity, Ferrihemocyanin-like)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of iron that can bind to ferric ferrocyanide in your blood, which helps assess iron availability and potential iron deficiency or overload conditions.

Quick summary

["This test may be used to evaluate iron metabolism and support diagnosis of conditions like anemia or hemochromatosis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
13513-7
Short code
Iron Mar K Ferrocyanide Stn
Synonyms
Iron Mar K Ferrocyanide Stn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
60
Ref high
170
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
potassium-ferrocyanide-stain
CPT
83540
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of iron bound to ferric ferrocyanide, a complex that reflects how much iron your blood can carry. This can indirectly indicate whether iron is being stored properly or if there’s an imbalance in iron levels.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms like fatigue, weakness, or signs of iron-related disorders. It could also be part of a broader evaluation for conditions affecting iron metabolism.

Common Conditions Monitored

This test is less commonly used alone but may be part of a panel to monitor iron deficiency anemia, hemochromatosis, or other iron-related disorders. It helps assess functional iron status rather than just total iron levels.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The sample is processed to separate serum (liquid part of blood without clotting factors) for testing. This test does not require fasting.

Reference range

NCBI: Serum Iron Male 65-180; Female 50-170 µg/dLN/A

Specimen: serum

Fasting for 12 hours preferred. Iron supplements should be stopped 24 hours before if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Iron Metabolism and Anemia

Short name

Iron Binding Capacity (Serum)

Frequently asked questions

How is this test different from a standard iron panel?
This test specifically measures iron binding capacity using ferric ferrocyanide, which is distinct from traditional iron tests like serum iron or total iron-binding capacity (TIBC). It provides insight into how well iron is transported in the bloodstream, which can differ from total iron stores.
Can this test replace other iron tests like ferritin or TIBC?
No, this test is supplementary. Ferritin measures stored iron, while TIBC assesses total iron-binding capacity. Together, they help diagnose iron deficiency or overload, but results should be interpreted alongside clinical symptoms and other tests.
What does a low or high result mean?
A low result may suggest iron deficiency or poor iron absorption, while a high result could indicate conditions like hemochromatosis or acute inflammation. Results should be evaluated by your healthcare provider in the context of your overall health and symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy