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Serum Iron Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of iron present in your blood serum, which is important for making hemoglobin—the protein in red blood cells that carries oxygen throughout your body.

Quick summary

["Iron levels help assess your risk of anemia or iron overload."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
110269-8
Short code
Iron Msmt SerPl
Synonyms
Iron Msmt SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
60
Ref high
170
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83540
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Iron’s Role in Your Body?

Iron is a vital mineral that helps your body produce hemoglobin, the protein in red blood cells that transports oxygen from your lungs to the rest of your body. Low iron levels can lead to fatigue, weakness, or anemia, while very high levels may cause health issues like organ damage or iron toxicity.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like extreme tiredness, pale skin, shortness of breath, or unusual fatigue. It may also be done to check for iron deficiency (low iron) or iron overload (hemochromatosis) before surgery, during pregnancy, or if you have certain medical conditions like gastrointestinal disorders.

What to Expect Before the Test

No special preparation is usually needed, but your doctor might ask you to avoid certain supplements (like iron or multivitamins) for a few days before testing. You may have a simple blood draw from a vein in your arm.

What Happens During the Test?

A healthcare professional will clean your arm’s skin, insert a small needle into a vein, and draw a small amount of blood. The process usually takes just a few minutes, and you may feel a slight pinch. The blood sample is then sent to a lab for analysis.

Reference range

NCBI: Serum Iron Male 65-180; Female 50-170 µg/dLN/A

Specimen: serum

Fasting for 12 hours preferred. Iron supplements should be stopped 24 hours before if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

How Your Results May Affect Your Health

Short name

Iron Level

Frequently asked questions

Low iron levels (anemia) can cause fatigue, weakness, or pale skin. High iron levels may indicate hemochromatosis or other conditions requiring medical attention. Your doctor will discuss results in the context of your overall health and symptoms.
What does a low iron level mean? Your doctor may recommend dietary changes, iron supplements, or further testing to identify the cause, such as blood loss from menstruation, poor diet, or gastrointestinal issues.
What does a high iron level mean? High iron levels may require lifestyle adjustments (like reducing red meat intake) or medical treatment to prevent organ damage. Your doctor may also check for conditions like hemochromatosis.
Can iron levels change with diet? Yes, certain foods (like leafy greens, lean meats, or fortified cereals) can affect iron levels. Avoiding excessive vitamin C with iron-rich foods may help prevent iron absorption issues.
How often should I get this test? Your doctor will determine frequency based on your health status, symptoms, or risk factors (e.g., pregnancy, chronic illness). Regular monitoring may be needed if you have conditions like anemia or hemochromatosis.
Is there anything I should do after the test? After the blood draw, apply gentle pressure to the site to stop bleeding. Avoid strenuous activity for a few hours. If you experience excessive bruising or pain, contact your doctor.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy